Case series: A possible association of relative peripheral refraction and lattice degeneration in patients with high myopia

Optom Vis Sci. 2026 Mar;103(3):e70019. doi: 10.1002/ovs2.70019.

ABSTRACT

PURPOSE: This case series aims to assess the potential relationship between relative peripheral hyperopia and the presence of lattice degeneration in individuals with myopia.

CASE REPORTS: We present three cases of individuals with high myopia, aged 11 and 52 years, who were diagnosed with lattice degeneration. The areas of relative peripheral hyperopia were found to correlate with the quadratic location of lattice degeneration lesions.

CONCLUSIONS: These observations suggest a potential association between relative peripheral refraction and the development of lattice degeneration in the retina. Relative peripheral hyperopia may serve as a potential marker to detect early pathological changes associated with myopia, particularly lattice degeneration. Longitudinal studies are warranted to validate these findings and further explore their clinical implications.

PMID:42020347 | DOI:10.1002/ovs2.70019